sry box transcription factor 2 (Proteintech)
Structured Review

Sry Box Transcription Factor 2, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 474 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sry+box+transcription+factor+2/SOX2+Antibody/pmc12983126-95-28-37
Average 96 stars, based on 474 article reviews
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1) Product Images from "Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation"
Article Title: Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation
Journal: Oncology Reports
doi: 10.3892/or.2026.9086
Figure Legend Snippet: Knockdown of CCT2 inhibits STAT3 signaling activation in hepatocellular carcinoma cells. The protein levels of STAT3, p-STAT3, MCL1, MMP2 and SOX2 in (A) Huh-7 and (B) HCCLM3 cells were measured by western blotting. The protein levels of (C) p-STAT3, (D) MCL1, (E) MMP2 and (F) SOX2 in subcutaneous tumor tissue were detected by immunohistochemical staining. *P<0.05, **P<0.01 vs. sh-NC. CCT2, chaperonin containing TCP1 subunit 2; sh, short hairpin; NC, negative control; p, phosphorylated; MCL1, myeloid cell leukemia sequence 1; SOX2, SRY-box transcription factor 2.
Techniques Used: Knockdown, Activation Assay, Western Blot, Immunohistochemical staining, Staining, Negative Control, Sequencing
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Sequencing:Article Title: Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation. Article Snippet: .. The primary antibodies were as follows: CCT2 (cat. no. 24896‐1‐AP), β‐actin (cat. no. 66009‐1‐Ig), MMP2 (cat. no. 10373‐2‐AP), myeloid cell leukemia sequence 1 (MCL1; cat. no. 16225‐1‐AP) and Article Title: Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation Article Snippet: .. The primary antibodies were as follows: CCT2 (cat. no. 24896-1-AP), β-actin (cat. no. 66009-1-Ig), MMP2 (cat. no. 10373-2-AP), myeloid cell leukemia sequence 1 (MCL1; cat. no. 16225-1-AP) and Incubation:Article Title: Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury. Article Snippet: The combination of cranial radiotherapy and chemotherapy may cause brain damage and cognitive dysfunction, therefore developing protective strategies for the treatment of chemoradiotherapy-induced brain injury is of great significance.. Deferoxamine is an efficient iron chelator to inhibit ferroptosis which induced by radiotherapy and chemotherapy, but it has low oral bioavailability and difficulty in crossing the blood brain barrier (BBB), which limit its clinical translation.. Herein, we constructed an orally microalgae-metal-organic framework (MOF) integrated drug delivery system (DFO@MOF@SP) for the protection of chemoradiotherapy-induced ferroptosisrelated brain injury. |